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藥靶細胞株 > kinase激酶細胞株 > CBP73373KRAS G12C-A59S/BaF3

KRAS G12C-A59S/BaF3
名稱 KRAS G12C-A59S/BaF3
型號 CBP73373
報價
特點 KRAS G12C-A59S/BaF3,凍存條件:90% FBS+10% DMSO
  • 詳細內容
CBP73373
I. Introduction

Cell Line Name:

KRAS G12C-A59S/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS+2ug/ml puromycin

Mycoplasma Status:

Negative

II.Background

KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

III. Representative Data

1.Sanger of KRAS G12C-A59S/BaF3

CBP73373 sanger-1.jpg

Figure 1. KRAS(NM_033360.4):c.34G>T p.G12C

CBP73373 sanger-2.jpg

Figure 2. KRAS(NM_004985.5):c.175G>T p.A59S

2. Anti-proliferation assay

CBP73373 數(shù)據(jù)圖.jpg

Figure 3. CTG Proliferation Assay of KRAS G12C/A59S BaF3 Cells (C1).


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